' 
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.9
USERS' SCORE
Good
Based on 7 Reviews
8.5
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Vitamin C (from culture of Saccharomyces cerevisiae)
60 mg
67%
Zinc (from Brown Rice Chelate)
30 mg
273%
Raw Organic Fruit & Vegetable BlendOrganic Apple (fruit), Organic Beet (root), Organic Broccoli (stalk & flower), Organic Carrot (root), Organic Spinach (leaf), Organic Tomato (fruit), Organic Strawberry (fruit), Organic Tart Cherry (fruit), Organic Blackberry (fruit), Organic Green Bell Pepper (fruit), Organic Brussels Sprout (leaf), Organic Blueberry (fruit), Organic Ginger (root), Organic Garlic (bulb), Organic Green Onion (bulb), Organic Raspberry (fruit), Organic Parsley (leaf), Organic Cauliflower (flower & stem), Organic Red Cabbage (leaf), Organic Kale (leaf), Organic Cucumber (gourd), Organic Celery (stalk), Organic Asparagus (flower & stem)
166 mg
+
Trace Mineral BlendRaw Organic Spirulina, Raw Organic Cracked-Wall Chlorella, Ancient Peat (Trace Minerals)
150 mg
+
Raw Probiotic & Enzyme BlendLipase, Protease, Aspergillopepsin, beta-Glucanase, Cellulase, Bromelain, Phytase, Lactase, Papain, Peptidase, Pectinase, Hemicellulase, Xylanase, [Lactobacillus bulgaricus, Lactobacillus plantarum] (500 Million CFU)
60 mg
+
Top Medical Research Studies
9
Zinc counters heart cell injury
Zn protects H9C2 cardiomyocytes by alleviating MAMs-associated apoptosis and calcium signaling dysregulation.
Highly relevant to cardiovascular health
We set out to investigate how zinc might help protect heart cells from damage caused by a lack of blood flow, known as myocardial ischemia-reperfusion injury (MIRI). Using H9C2 cells, which are derived from rat heart tissue, we simulated this injury by depriving these cells of oxygen and then reintroducing it while treating them with zinc.
Through this process, we found that zinc treatment significantly increased cell viability compared to those that did not receive zinc. Cells exposed to ischemia showed typical signs of trauma, like heightened levels of apoptosis—or programmed cell death—and calcium overload, which can further damage cells.
Interestingly, zinc seemed to tackle these issues by lowering the levels of certain proteins related to cell death. It also played a role in regulating calcium levels by interacting with various cellular pathways. In fact, when we silenced specific proteins involved in these pathways, the protective benefits of zinc were even more pronounced.
Our findings suggest that zinc can relieve the harmful effects of ischemia by mitigating cell death and regulating calcium overload, which offers hope for future treatments for heart-related conditions impacted by blood flow interruptions.
Through this process, we found that zinc treatment significantly increased cell viability compared to those that did not receive zinc. Cells exposed to ischemia showed typical signs of trauma, like heightened levels of apoptosis—or programmed cell death—and calcium overload, which can further damage cells.
Interestingly, zinc seemed to tackle these issues by lowering the levels of certain proteins related to cell death. It also played a role in regulating calcium levels by interacting with various cellular pathways. In fact, when we silenced specific proteins involved in these pathways, the protective benefits of zinc were even more pronounced.
Our findings suggest that zinc can relieve the harmful effects of ischemia by mitigating cell death and regulating calcium overload, which offers hope for future treatments for heart-related conditions impacted by blood flow interruptions.
Read More
8
Zinc and ANP support heart health
ANP Increases Zn Accumulation During Reperfusion in Ex Vivo and In Vivo Hearts.
Relevant to zinc and heart disease
We explored the relationship between atrial natriuretic peptide (ANP) and zinc, particularly how they work together to protect the heart during reperfusion after ischemia. The study involved comparing various experimental rats and mice, as well as assessing plasma samples from patients experiencing heart-related conditions.
Our findings highlighted that ANP significantly boosts zinc levels during the crucial period of reperfusion. This increase in zinc appears to protect heart cells from damage by helping to maintain mitochondrial health, effectively reducing the size of heart tissue injuries. We observed that when ANP was administered alone, it improved heart function, but combining it with a substance that removes zinc led to poorer outcomes.
We also noted that ANP works through a specific signaling pathway (the PI3K pathway) to decrease levels of a zinc transporter, ZnT8, which is upregulated during reperfusion injury. Interestingly, both ANP and zinc had a role in regulating important proteins linked to heart health. Overall, our research suggests that managing zinc levels through ANP treatment can help shield the heart from the harsh effects of ischemia/reperfusion injury.
Our findings highlighted that ANP significantly boosts zinc levels during the crucial period of reperfusion. This increase in zinc appears to protect heart cells from damage by helping to maintain mitochondrial health, effectively reducing the size of heart tissue injuries. We observed that when ANP was administered alone, it improved heart function, but combining it with a substance that removes zinc led to poorer outcomes.
We also noted that ANP works through a specific signaling pathway (the PI3K pathway) to decrease levels of a zinc transporter, ZnT8, which is upregulated during reperfusion injury. Interestingly, both ANP and zinc had a role in regulating important proteins linked to heart health. Overall, our research suggests that managing zinc levels through ANP treatment can help shield the heart from the harsh effects of ischemia/reperfusion injury.
Read More
8
Zinc effects on sleep in CVD
Role of toxic and essential elements in sleep duration of patients with cardiovascular diseases.
Relevant relationship noted
We investigated how zinc levels may influence sleep duration in patients with cardiovascular diseases (CVDs). Our study included 150 participants from the Ravansar Non-Communicable Disease Cohort Study, where we measured serum concentrations of zinc and other elements, including essential minerals and toxic metals.
A significant finding was that we observed a strong correlation between higher zinc concentrations and optimal sleep duration. Specifically, the data indicated that as zinc levels increased, the likelihood of achieving an appropriate sleep duration of 7 to 8 hours also increased.
However, when we looked deeper into the data, we did not find significant differences in the serum concentrations of both essential and toxic elements across different sleep duration categories. This suggests that while zinc may play a role in regulating sleep duration, it does not entirely account for sleep issues among CVD patients.
Ultimately, our results encourage further exploration of zinc's impact, particularly as it relates to sleep quality and overall health in individuals with cardiovascular conditions.
A significant finding was that we observed a strong correlation between higher zinc concentrations and optimal sleep duration. Specifically, the data indicated that as zinc levels increased, the likelihood of achieving an appropriate sleep duration of 7 to 8 hours also increased.
However, when we looked deeper into the data, we did not find significant differences in the serum concentrations of both essential and toxic elements across different sleep duration categories. This suggests that while zinc may play a role in regulating sleep duration, it does not entirely account for sleep issues among CVD patients.
Ultimately, our results encourage further exploration of zinc's impact, particularly as it relates to sleep quality and overall health in individuals with cardiovascular conditions.
Read More
Most Useful Reviews
8.8
Aids recovery
Zinc is an excellent protector against viruses. At the first indication of a cold, further progression of the disease can be prevented. Zinc assisted me in managing covid, and I experienced a mild illness.
Read More
7.5
Supports immunity
I purchased it for disease prevention during winter, and the medication succeeded in its purpose. I intend to take it periodically to bolster my immune system.
Read More
9.5
Pandemic support
The disease passed quickly for me and was one of my saviours during the pandemic. Thank you!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.9
- All Researches
9
Zinc nanoparticles reduce heart damage
Role of zinc oxide nanoparticles supplementation on alleviate side effects of cisplatin induced cardiotoxicity in rats.
Moderate relevance to cardiovascular research
We focused our research on how zinc oxide nanoparticles (ZnONPs) might help reduce heart damage caused by cisplatin, a well-known chemotherapy drug. In this study, we used rats divided into different groups, some receiving varying doses of ZnONPs and others serving as control groups.
Our findings indicated that as the dosage of ZnONPs increased up to 50 mg/kg, there was a marked improvement in cardiovascular markers. We observed reduced levels of oxidative stress, inflammation, and cell damage in the heart tissues of those treated with ZnONPs. More specifically, measures related to heart tissue health and serum biomarkers showed that rats receiving higher doses exhibited recovery similar to that of healthy rats.
Overall, we concluded that ZnONPs serve as a protective agent against cisplatin-induced cardiotoxicity, showcasing their potential in improving heart health during cancer treatment.
Our findings indicated that as the dosage of ZnONPs increased up to 50 mg/kg, there was a marked improvement in cardiovascular markers. We observed reduced levels of oxidative stress, inflammation, and cell damage in the heart tissues of those treated with ZnONPs. More specifically, measures related to heart tissue health and serum biomarkers showed that rats receiving higher doses exhibited recovery similar to that of healthy rats.
Overall, we concluded that ZnONPs serve as a protective agent against cisplatin-induced cardiotoxicity, showcasing their potential in improving heart health during cancer treatment.
Read More
9
Zinc counters heart cell injury
Zn protects H9C2 cardiomyocytes by alleviating MAMs-associated apoptosis and calcium signaling dysregulation.
Highly relevant to cardiovascular health
We set out to investigate how zinc might help protect heart cells from damage caused by a lack of blood flow, known as myocardial ischemia-reperfusion injury (MIRI). Using H9C2 cells, which are derived from rat heart tissue, we simulated this injury by depriving these cells of oxygen and then reintroducing it while treating them with zinc.
Through this process, we found that zinc treatment significantly increased cell viability compared to those that did not receive zinc. Cells exposed to ischemia showed typical signs of trauma, like heightened levels of apoptosis—or programmed cell death—and calcium overload, which can further damage cells.
Interestingly, zinc seemed to tackle these issues by lowering the levels of certain proteins related to cell death. It also played a role in regulating calcium levels by interacting with various cellular pathways. In fact, when we silenced specific proteins involved in these pathways, the protective benefits of zinc were even more pronounced.
Our findings suggest that zinc can relieve the harmful effects of ischemia by mitigating cell death and regulating calcium overload, which offers hope for future treatments for heart-related conditions impacted by blood flow interruptions.
Through this process, we found that zinc treatment significantly increased cell viability compared to those that did not receive zinc. Cells exposed to ischemia showed typical signs of trauma, like heightened levels of apoptosis—or programmed cell death—and calcium overload, which can further damage cells.
Interestingly, zinc seemed to tackle these issues by lowering the levels of certain proteins related to cell death. It also played a role in regulating calcium levels by interacting with various cellular pathways. In fact, when we silenced specific proteins involved in these pathways, the protective benefits of zinc were even more pronounced.
Our findings suggest that zinc can relieve the harmful effects of ischemia by mitigating cell death and regulating calcium overload, which offers hope for future treatments for heart-related conditions impacted by blood flow interruptions.
Read More
8
Zinc and ANP support heart health
ANP Increases Zn Accumulation During Reperfusion in Ex Vivo and In Vivo Hearts.
Relevant to zinc and heart disease
We explored the relationship between atrial natriuretic peptide (ANP) and zinc, particularly how they work together to protect the heart during reperfusion after ischemia. The study involved comparing various experimental rats and mice, as well as assessing plasma samples from patients experiencing heart-related conditions.
Our findings highlighted that ANP significantly boosts zinc levels during the crucial period of reperfusion. This increase in zinc appears to protect heart cells from damage by helping to maintain mitochondrial health, effectively reducing the size of heart tissue injuries. We observed that when ANP was administered alone, it improved heart function, but combining it with a substance that removes zinc led to poorer outcomes.
We also noted that ANP works through a specific signaling pathway (the PI3K pathway) to decrease levels of a zinc transporter, ZnT8, which is upregulated during reperfusion injury. Interestingly, both ANP and zinc had a role in regulating important proteins linked to heart health. Overall, our research suggests that managing zinc levels through ANP treatment can help shield the heart from the harsh effects of ischemia/reperfusion injury.
Our findings highlighted that ANP significantly boosts zinc levels during the crucial period of reperfusion. This increase in zinc appears to protect heart cells from damage by helping to maintain mitochondrial health, effectively reducing the size of heart tissue injuries. We observed that when ANP was administered alone, it improved heart function, but combining it with a substance that removes zinc led to poorer outcomes.
We also noted that ANP works through a specific signaling pathway (the PI3K pathway) to decrease levels of a zinc transporter, ZnT8, which is upregulated during reperfusion injury. Interestingly, both ANP and zinc had a role in regulating important proteins linked to heart health. Overall, our research suggests that managing zinc levels through ANP treatment can help shield the heart from the harsh effects of ischemia/reperfusion injury.
Read More
8
Zinc effects on sleep in CVD
Role of toxic and essential elements in sleep duration of patients with cardiovascular diseases.
Relevant relationship noted
We investigated how zinc levels may influence sleep duration in patients with cardiovascular diseases (CVDs). Our study included 150 participants from the Ravansar Non-Communicable Disease Cohort Study, where we measured serum concentrations of zinc and other elements, including essential minerals and toxic metals.
A significant finding was that we observed a strong correlation between higher zinc concentrations and optimal sleep duration. Specifically, the data indicated that as zinc levels increased, the likelihood of achieving an appropriate sleep duration of 7 to 8 hours also increased.
However, when we looked deeper into the data, we did not find significant differences in the serum concentrations of both essential and toxic elements across different sleep duration categories. This suggests that while zinc may play a role in regulating sleep duration, it does not entirely account for sleep issues among CVD patients.
Ultimately, our results encourage further exploration of zinc's impact, particularly as it relates to sleep quality and overall health in individuals with cardiovascular conditions.
A significant finding was that we observed a strong correlation between higher zinc concentrations and optimal sleep duration. Specifically, the data indicated that as zinc levels increased, the likelihood of achieving an appropriate sleep duration of 7 to 8 hours also increased.
However, when we looked deeper into the data, we did not find significant differences in the serum concentrations of both essential and toxic elements across different sleep duration categories. This suggests that while zinc may play a role in regulating sleep duration, it does not entirely account for sleep issues among CVD patients.
Ultimately, our results encourage further exploration of zinc's impact, particularly as it relates to sleep quality and overall health in individuals with cardiovascular conditions.
Read More
7
Zinc's role in cardiovascular risk
Dietary zinc intake and 10-year atherosclerotic cardiovascular disease risk in diabetes mellitus patients: evidence from NHANES database.
Significant but needs further study
We explored the relationship between dietary zinc intake and the risk of atherosclerotic cardiovascular disease (ASCVD) in patients with diabetes mellitus (DM). Utilizing data from the National Health and Nutrition Examination Survey (NHANES) between 2007 and 2018, we calculated the 10-year ASCVD risk according to established clinical guidelines. Our analysis focused on dietary zinc intake based on food recall data from the participants.
The findings suggest that sufficient dietary zinc intake could positively influence cardiovascular health in diabetes patients. This is particularly important, as diabetes is closely linked with increased oxidative stress and inflammation, two factors that contribute to the development of heart disease. While we see an association between zinc and improved heart health, it's essential to note that further research is needed. Large-scale, well-designed prospective studies should aim to clarify the specific role of zinc in this context.
Overall, our results underscore the potential benefits of zinc for cardiovascular health, particularly in individuals managing diabetes. As we delve deeper into these associations, we aim to provide clearer guidance on how dietary choices can impact health outcomes for those living with diabetes.
The findings suggest that sufficient dietary zinc intake could positively influence cardiovascular health in diabetes patients. This is particularly important, as diabetes is closely linked with increased oxidative stress and inflammation, two factors that contribute to the development of heart disease. While we see an association between zinc and improved heart health, it's essential to note that further research is needed. Large-scale, well-designed prospective studies should aim to clarify the specific role of zinc in this context.
Overall, our results underscore the potential benefits of zinc for cardiovascular health, particularly in individuals managing diabetes. As we delve deeper into these associations, we aim to provide clearer guidance on how dietary choices can impact health outcomes for those living with diabetes.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
8.8
Aids recovery
Zinc is an excellent protector against viruses. At the first indication of a cold, further progression of the disease can be prevented. Zinc assisted me in managing covid, and I experienced a mild illness.
7.5
Supports immunity
I purchased it for disease prevention during winter, and the medication succeeded in its purpose. I intend to take it periodically to bolster my immune system.
9.5
Pandemic support
The disease passed quickly for me and was one of my saviours during the pandemic. Thank you!
9.5
Eases illness
I just fell ill yesterday, and the disease seems much milder. I would recommend it to others.
8.8
Enhances antiviral defence
One of the best offerings from a reputable company! The composition is excellent, derived from raw and whole foods! Zinc in picolinate form is absorbed significantly better (70-90%) than citrate or sulfate, with zinc oxide being the least effective. Besides zinc, it also includes vitamin C and extracts from berries, vegetables, and fruits. It’s better to take it after meals, as it may induce nausea. Zinc is a crucial component for the body's antiviral defence, and deficiency can lead to an increase in disease incidence, growth inhibition, and hair loss. It is shown to help ease and hasten recovery when taken at the first sign of a cold.
Read More
